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Ation of Ras-dependent signaling pathways by G14-coupled receptors requires the adaptor protein TPR1. J Cell Biochem. 2012;113(11):3486?7. 35. Liu AMF, Lo RKH, Lee MMK, Wang Y, Yeung WWS, Ho MKC, et al. G16 activates Ras by forming a complex with tetratricopeptide repeat 1 (TPR1) and Son of Sevenless (SOS). Cell Signal. 2010;22:1448?8. 36. Marty C, Browning DD, Ye RD. Identification of tetratricopeptide repeat 1 as an adaptor protein that interacts with heterotrimeric G proteins and the small GTPase Ras. Mol Cell Biol. 2003;23:3847?8. 37. Smrcka AV, Hepler JR, Brown KO, Sternweis PC. Regulation of polyphosphoinositide-specific phospholipase C activity by purified Gq. Science. 1991;251:804?. 38. Lee CH, Shin IC, Kang JC, Koh HC, Ha JH, Min CJ. Differential coupling of Gq family of G-protein to muscarinic M1 receptor and neurokinin-2 receptor. Arch Pharm Res. 1998;4:423?. 39. Medina R, Grishina G, Meloni EG, Muth TR, Berlot CH. Localization of the effector-specifying regions of Gi2 and Gq. J Biol Chem. 1996;271:24720?. 40. Ho MK, Yung LY, Chan JS, Chan JH, Wong CS, Wong YH. G14 links a variety of Gi and Gs-coupled receptors to the stimulation of phospholipase C. Br J Pharmacol. 2001;132(7):1431?0. 41. Offermanns S, Simon MI. G15 and G16 couple a wide variety of receptors to phospholipase C. J Biol Chem. 1995;270(25):15175?0. 42. Kostenis E. Is G 16 the optimal tool for fishing ligands of orphan G-protein-coupled receptors? Trends Pharmacol Sci. 2001;22(11):560?. 43. Linder ME, Middleton P, Hepler JR, Taussig R, Gilman AG, Mumby SM. Lipid modifications of G proteins: alpha subunits are palmitoylated. Proc Natl Acad Sci. 1993;90(8):3675?. 44. Pedone KH, Hepler PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/16474207 JR. The importance of N-terminal polycysteine and polybasic sequences for G14 and G16 palmitoylation, plasma membrane localization, and signaling function. J Biol Chem. 2007;282(35):25199?12. 45. Dohlman HG, Jones JC. Signal activation and inactivation by the G helical domain: a long-neglected partner in G protein signaling. Sci Signal. 2012;5(226):re2. 46. Day PW, Carman CV, Sterne-Marr R, Benovic JL, Wedegaertner PB. Differential interaction of GRK2 with members of the Gq family. Biochemistry. 2003;42(30):9176?4.Kwan et al. BMC Structural Biology (2015) 15:Page ROCK-IN-2 15 of47. Berlot CH, Bourne HR. Identification of effector-activating residues of Gs. Cell. 1992;68:911?2. 48. Grishina G, Berlot CH. Identification of common and distinct residues involved in the interaction of i2 and s with adenylyl cyclase. J Biol Chem. 1997;272:20619?6. 49. Coleman DE, Berghuis AM, Lee PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/8627573 E, Linder ME, Gilman AG, Sprang SR. Structures of active conformations of Gi1 and the mechanism of GTP hydrolysis. Science. 1994;265:1405?2. 50. Masters SB, Stroud RM, Bourne HR. Family of G protein chains: amphipathic analysis and predicted structure of functional domains. Protein Eng. 1986;1:47?4. 51. Noel JP, Hamm HE, Sigler PB. The 2.2 A crystal structure of transducin complexed with GTPS. Nature. 1993;366:654?3. 52. Remmers AE, Engel C, Liu M, Neubig RR. Interdomain interactions regulate GDP release from heterotrimeric G proteins. Biochemistry. 1999;38:13795?00. 53. Mixon MB, Lee E, Coleman DE, Berghuis AM, Gilman AG, Sprang SR. Tertiary and quaternary structural changes in Gi1 induced by GTP hydrolysis. Science. 1995;270:954?0. 54. Codina J, Birnbaumer L. Requirement for intramolecular domain interaction in activation of G protein subunit by aluminum fluoride and GDP but not by GTPS. J Biol Chem. 1994;269:29339?2. 55.

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